CBX5 Antibody (Center)

Synthetic Peptide

This gene encodes a highly conserved nonhistone protein,
which is a member of the heterochromatin protein family. The
protein is enriched in the heterochromatin and associated with
centromeres. The protein has a single N-terminal chromodomain which
can bind to histone proteins via methylated lysine residues, and a
C-terminal chromo shadow-domain (CSD) which is responsible for the
homodimerization and interaction with a number of
chromatin-associated nonhistone proteins. The encoded product is
involved in the formation of functional kinetochore through
interaction with essential kinetochore proteins. The gene has a
pseudogene located on chromosome 3. Multiple alternatively spliced
variants, encoding the same protein, have been identified.

Polyclonal

23468

Affinity Purified Rabbit Polyclonal Antibody (Pab)

CBX5 Antibody (Center) (Cat. #AP13779c) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the CBX5 antibody detected the CBX5 protein (arrow).

1:1000

M

22225

HUMAN

NP_001120793.1; NP_001120794.1; NP_036249.1