Hersteller |
Abcepta
|
Kategorie |
|
Typ |
Antibody Primary |
Specific against |
other |
Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Applikationen |
WB, IHC-P |
Menge |
80 ul |
Host |
Rabbit |
ArtNr |
ABC-AP13842a-ev |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Lieferbar |
|
Primary Accession |
P09086 |
Antigen Type |
Synthetic Peptide |
Application |
IHC-P, WB |
Bio Background |
POU2F2 is a transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3'). Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR. Isoform 5 activates the U2 small nuclear RNA (snRNA) promoter. |
Bio References |
Galetti, M., et al. Biochem. Pharmacol. 80(2):179-187(2010)Bailey, S.D., et al. Diabetes Care (2010) In press :Advani, A.S., et al. Leuk. Lymphoma 51(4):606-612(2010)Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Filipski, K.K., et al. Clin. Pharmacol. Ther. 86(4):396-402(2009) |
Clonality |
Polyclonal |
Clone/Animal Names |
RB33756 |
Gene ID |
5452 |
Gene Name |
|
Subtitle |
Affinity Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
H |
Legend image 1 |
POU2F2 Antibody (N-term) (Cat. #AP13842a) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the POU2F2 antibody detected the POU2F2 protein (arrow). |
Type image 1 |
WB |
Dilution image 1 |
1:1000 |
Legend image 2 |
POU2F2 Antibody (N-term) (AP13842a)immunohistochemistry analysis in formalin fixed and paraffin embedded human testis carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of POU2F2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
Type image 2 |
IHC-P |
Dilution image 2 |
1:10~50 |
Other Accession |
Q29013; Q00196; NP_002689.1 |
Predicted |
M, Pig |
Isotype |
Rabbit Ig |
Calculated MW |
51209 |
Antigen Region |
10-39 |
Antigen Source |
HUMAN |
Target/Specificity |
This POU2F2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 10-39 amino acids from the N-terminal region of human POU2F2. |
NCBI Accession |
NP_001193954.1; NP_001193955.1; NP_001234923.1; NP_002689.1 |
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