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Mouse Epha2 Antibody (Center)

Mouse Epha2 Antibody (Center)

ArtNr	ABC-AP14619c-ev
Hersteller	Abcepta
Menge	80 ul
Kategorie	Oncology Neuroscience Neural Signaling Neural Adhesion Molecules Antibodies By Cell Type Carcinoma Hematology Lymphoma Myeloma Sarcoma Western Blot Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	WB
Specific against	Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Citations	Islam, S., et al. Dig. Dis. Sci. 55(9):2478-2488(2010) Kim, J., et al. Mol. Cell. Biol. 30(7):1582-1592(2010) Zirzow, S., et al. Dev. Biol. 336(2):145-155(2009) Jun, G., et al. PLoS Genet. 5 (7), E1000584 (2009): North, H.A., et al. Development 136(14):2467-2476(2009)
NCBI	NP_034269.2
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Ephrin type-A receptor 2,Epithelial cell kinase,Tyrosine-protein kinase receptor ECK,Tyrosine-protein kinase receptor MPK-5,Tyrosine-protein kinase receptor SEK-2,Epha2,Eck,Myk2,Sek2
Similar products	Epha2, Eck, Myk2, Sek2, Ephrin type-A receptor 2, Epithelial cell kinase, Tyrosine-protein kinase receptor ECK, Tyrosine-protein kinase receptor MPK-5, Tyrosine-protein kinase receptor SEK-2
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Manufacturer - Category	Primary Antibodies; Cardiovascular; Neuroscience
Manufacturer - Targets	This Mouse Epha2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 296-323 amino acids from the Central region of mouse Epha2.
Bio Background	Receptor for members of the ephrin-A family. Binds to ephrin-A1, -A3, -A4 and -A5. Induces apoptosis in a TP53/p53-independent, caspase-8-dependent manner (By similarity). Plays an important role in angiogenesis and tumor neovascularization. The recruitement of VAV2, VAV3 and PI3-kinase p85 subunit by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly. May function in distinctive aspects of pattern formation and subsequently in development of several fetal tissues. May be involved in cell-cell interactions guiding early hindbrain development.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB34764
Gene Name	Epha2
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	M
Calculated Molecular Weight	108852
Antigen Source	MOUSE
Antigen Region	296-323
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	WB: 1:1000
Antigen Type	Synthetic Peptide

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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