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LRP5 Antibody (C-term)

ArtNr ABC-AP14655b
Hersteller Abcepta
Menge 400 ul
Kategorie
Typ Antibody Polyclonal
Applikationen WB
Specific against Mouse (Murine, Mus musculus)
Host Rabbit
Isotype IgG
Citations Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Lee, D.Y., et al. Menopause 17(5):1064-1070(2010)
Liu, J.M., et al. J. Clin. Endocrinol. Metab. 95 (9), E112-E120 (2010):
Paternoster, L., et al. J. Clin. Endocrinol. Metab. 95(8):3940-3948(2010)
Stathopoulou, M.G., et al. J Am Diet Assoc 110(7):1078-1083(2010)
NCBI NP_002326.2
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Low-density lipoprotein receptor-related protein 5,LRP-5,LRP5,LR3,LRP7
Similar products LRP5, LR3, LRP7, Low-density lipoprotein receptor-related protein 5, LRP-5
Lieferbar
Manufacturer - Category
Primary Antibodies; Cardiovascular; Metabolism; Neuroscience; Signal Transduction; Anti-Wnt-Pathway (plus Lgr5) Antibodies
Manufacturer - Targets
This LRP5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1163-1190 amino acids from the C-terminal region of human LRP5.
Bio Background
This gene encodes a transmembrane low-density lipoproteinreceptor that binds and internalizes ligands in the process ofreceptor-mediated endocytosis. This protein also acts as aco-receptor with Frizzled protein family members for transducingsignals by Wnt proteins and was originally cloned on the basis ofits association with type 1 diabetes mellitus in humans. Thisprotein plays a key role in skeletal homeostasis and many bonedensity related diseases are caused by mutations in this gene.Mutations in this gene also cause familial exudativevitreoretinopathy.
Clonality
Polyclonal
Polyclonal Antibody Additonal Information
RB32191
Gene Name
LRP5 {ECO:0000303|PubMed:24706814, ECO:0000312|HGNC:HGNC:6697}
Subtitle
Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
M
Calculated Molecular Weight
179145
Antigen Source
HUMAN
Antigen Region
1163-1190
Formulation
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution
WB: 1:1000
Antigen Type
Synthetic Peptide

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 400 ul
Lieferbar: In stock
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