KCNQ3 Antibody (C-term)

NP_004510.1

The M channel is a slowly activating and deactivating
potassium channel that plays a critical role in the regulation of
neuronal excitability. The M channel is formed by the association
of the protein encoded by this gene and one of two related proteins
encoded by the KCNQ2 and KCNQ5 genes, both integral membrane
proteins. M channel currents are inhibited by M1 muscarinic
acetylcholine receptors and activated by retigabine, a novel
anti-convulsant drug. Defects in this gene are a cause of benign
familial neonatal convulsions type 2 (BFNC2), also known as
epilepsy, benign neonatal type 2 (EBN2).

3786

M

651-679

This KCNQ3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 651-679 amino acids from the C-terminal region of human KCNQ3.