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KCNA1 Antibody (Center)

ArtNr ABC-AP14746c-ev
Hersteller Abcepta
Menge 80 ul
Kategorie
Typ Antibody Polyclonal
Applikationen WB, IHC-P
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Citations Graves, T.D., et al. Neurology 75(4):367-372(2010)
Bailey, S.D., et al. Diabetes Care (2010) In press:
van der Wijst, J., et al. J. Biol. Chem. 285(1):171-178(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Kim, E., et al. Nature 378(6552):85-88(1995)
NCBI NP_000208.2
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Potassium voltage-gated channel subfamily A member 1,Voltage-gated K(+) channel HuKI,Voltage-gated potassium channel HBK1,Voltage-gated potassium channel subunit Kv11,KCNA1
Similar products KCNA1, Potassium voltage-gated channel subfamily A member 1, Voltage-gated K(+) channel HuKI, Voltage-gated potassium channel HBK1, Voltage-gated potassium channel subunit Kv11
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Manufacturer - Category
Primary Antibodies; Neuroscience; SARS-Human interaction partners
Manufacturer - Targets
This KCNA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 172-201 amino acids from the Central region of human KCNA1.
Bio Background
This gene encodes a voltage-gated delayed potassiumchannel that is phylogenetically related to the Drosophila Shakerchannel. The encoded protein has six putative transmembranesegments (S1-S6), and the loop between S5 and S6 forms the pore andcontains the conserved selectivity filter motif (GYGD). Thefunctional channel is a homotetramer. The N-terminus of the channelis associated with beta subunits that can modify the inactivationproperties of the channel as well as affect expression levels. TheC-terminus of the channel is complexed to a PDZ domain protein thatis responsible for channel targeting. Mutations in this gene havebeen associated with myokymia with periodic ataxia (AEMK).
Clonality
Polyclonal
Polyclonal Antibody Additonal Information
RB34947
Gene Name
KCNA1
Subtitle
Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H
Predicted Reactivity
M, Rat
Calculated Molecular Weight
56466
Antigen Source
HUMAN
Antigen Region
172-201
Formulation
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution
WB: 1:1000
IHC-P: 1:10~50
Antigen Type
Synthetic Peptide

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 80 ul
Lieferbar: In stock
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