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ACTA1/Alpha-actin Antibody (C-term)

ArtNr ABC-AP14779b
Hersteller Abcepta
Menge 400 ul
Kategorie
Typ Antibody Polyclonal
Applikationen WB, FC, IF, IHC-P
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Citations Kim, E.Y., et al. Am. J. Physiol. Renal Physiol. 299 (3), F594-F604 (2010):
Haigh, S.E., et al. Neuromuscul. Disord. 20(6):363-374(2010)
Yu, G., et al. J Clin Neurosci 17(6):766-769(2010)
Yu, C.H., et al. PLoS ONE 5 (7), E11878 (2010):
Licastro, F., et al. Curr. Pharm. Des. 16(7):783-788(2010)
NCBI NP_001091.1
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Actin,alpha skeletal muscle,Alpha-actin-1,ACTA1,ACTA
Similar products Actin, ACTA1, ACTA, alpha skeletal muscle, Alpha-actin-1
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Manufacturer - Category
Crown Antibodies; Primary Antibodies; Cancer; Cardiovascular; Signal Transduction
Manufacturer - Targets
This ACTA1/Alpha-actin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 346-375 amino acids from the C-terminal region of human ACTA1/Alpha-actin.
Bio Background
The product encoded by this gene belongs to the actinfamily of proteins, which are highly conserved proteins that play arole in cell motility, structure and integrity. Alpha, beta andgamma actin isoforms have been identified, with alpha actins beinga major constituent of the contractile apparatus, while beta andgamma actins are involved in the regulation of cell motility. Thisactin is an alpha actin that is found in skeletal muscle. Mutationsin this gene cause nemaline myopathy type 3, congenital myopathywith excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseasesthat lead to muscle fiber defects.
Clonality
Polyclonal
Polyclonal Antibody Additonal Information
RB35391
Gene Name
ACTA1
Subtitle
Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H
Predicted Reactivity
X, B, C, M, Rb, Rat, Pig
Calculated Molecular Weight
42051
Antigen Source
HUMAN
Antigen Region
346-375
Formulation
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution
IF: 1:10~50
WB: 1:1000
IHC-P: 1:10~50
FC: 1:10~50
Antigen Type
Synthetic Peptide

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 400 ul
Lieferbar: In stock
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