GPC3 Antibody (C-term)

Synthetic Peptide

Cell surface heparan sulfate proteoglycans are composed of
a membrane-associated protein core substituted with a variable
number of heparan sulfate chains. Members of the glypican-related
integral membrane proteoglycan family (GRIPS) contain a core
protein anchored to the cytoplasmic membrane via a glycosyl
phosphatidylinositol linkage. These proteins may play a role in the
control of cell division and growth regulation. The protein encoded
by this gene can bind to and inhibit the dipeptidyl peptidase
activity of CD26, and it can induce apoptosis in certain cell
types. Deletion mutations in this gene are associated with
Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia
syndrome. Alternative splicing results in multiple transcript
variants.

Polyclonal

2719

Affinity Purified Rabbit Polyclonal Antibody (Pab)

GPC3 Antibody (C-term) (Cat. #AP14822b) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the GPC3 antibody detected the GPC3 protein (arrow).

1:1000

Rabbit Ig

465-494

This GPC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 465-494 amino acids from the C-terminal region of human GPC3.