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GPC3 Antibody (C-term)

GPC3 Antibody (C-term)

ArtNr	ABC-AP14822b
Hersteller	Abcepta
Menge	400 ul
Kategorie	Oncology Neuroscience Neural Signaling Antibodies By Cell Type Blastoma Carcinoma Western Blot Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	WB
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Lai, J.P., et al. Hepatology 52(5):1680-1689(2010) Sakurai, M., et al. Gynecol. Oncol. 119(2):332-336(2010) Zynger, D.L., et al. Histopathology 56(6):750-757(2010) Davoodi, J., et al. Proteomics 7(13):2300-2310(2007) Hsu, H.C., et al. Cancer Res. 57(22):5179-5184(1997)
NCBI	NP_001158089.1,NP_001158091.1,NP_004475.1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Glypican-3,GTR2-2,Intestinal protein OCI-5,MXR7,Secreted glypican-3,GPC3,OCI5
Similar products	Glypican-3, GPC3, OCI5, GTR2-2, Intestinal protein OCI-5, MXR7, Secreted glypican-3
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Manufacturer - Category	Primary Antibodies; Cancer; Developmental Biology; Signal Transduction
Manufacturer - Targets	This GPC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 465-494 amino acids from the C-terminal region of human GPC3.
Bio Background	Cell surface heparan sulfate proteoglycans are composed ofa membrane-associated protein core substituted with a variablenumber of heparan sulfate chains. Members of the glypican-relatedintegral membrane proteoglycan family (GRIPS) contain a coreprotein anchored to the cytoplasmic membrane via a glycosylphosphatidylinositol linkage. These proteins may play a role in thecontrol of cell division and growth regulation. The protein encodedby this gene can bind to and inhibit the dipeptidyl peptidaseactivity of CD26, and it can induce apoptosis in certain celltypes. Deletion mutations in this gene are associated withSimpson-Golabi-Behmel syndrome, also known as Simpson dysmorphiasyndrome. Alternative splicing results in multiple transcriptvariants.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB34500
Gene Name	GPC3
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Calculated Molecular Weight	65563
Antigen Source	HUMAN
Antigen Region	465-494
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	WB: 1:1000
Antigen Type	Synthetic Peptide

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 400 ul

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