Vergleich

GLRB Antibody (N-term)

Hersteller Abcepta
Kategorie
Typ Antibody Primary
Specific against other
Isotype Ig
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen WB
Menge 400 ul
Host Rabbit
ArtNr ABC-AP14931a
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
Primary Accession
P48167
Antigen Type
Synthetic Peptide
Application
WB
Bio Background
This gene encodes the beta subunit of the glycine
receptor, which is a pentamer composed of alpha and beta subunits.
The receptor functions as a neurotransmitter-gated ion channel,
which produces hyperpolarization via increased chloride conductance
due to the binding of glycine to the receptor. Mutations in this
gene cause startle disease, also known as hereditary hyperekplexia
or congenital stiff-person syndrome, a disease characterized by
muscular rigidity. Alternative splicing results in multiple
transcript variants.
Bio References
Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34(5):800-812(2010)
Wheeler, H.E., et al. PLoS Genet. 5 (10), E1000685 (2009) :
Ziegler, E., et al. Naunyn Schmiedebergs Arch. Pharmacol. 380(4):277-291(2009)
Tabakoff, B., et al. BMC Biol. 7, 70 (2009) :
Ahrens, J., et al. Pharmacology 83(4):217-222(2009)
Clonality
Polyclonal
Clone/Animal Names
RB35424
Gene ID
2743
Gene Name
GLRB
Subtitle
Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H
Legend image 1
Western blot analysis of lysate from Jurkat cell line, using GLRB Antibody (N-term)(Cat. #AP14931a). AP14931a was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane.
Type image 1
WB
Dilution image 1
1:1000
Other Accession
P20781; P48168; Q9GJS9; NP_001159532.1; NP_000815.1
Predicted
B, M, Rat
Isotype
Rabbit Ig
Calculated MW
56122
Antigen Region
103-132
Antigen Source
HUMAN
Target/Specificity
This GLRB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 103-132 amino acids from the N-terminal region of human GLRB.
NCBI Accession
NP_000815.1; NP_001159532.1; NP_001159533.1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 400 ul
Lieferbar: In stock
lieferbar

Lieferung vsl. bis 04.07.2024 

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