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MOV10 Antibody (N-term)

MOV10 Antibody (N-term)

ArtNr	ABC-AP14933a-ev
Hersteller	Abcepta
Menge	80 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen	WB, IHC-P
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	MOV10, KIAA1631, Putative helicase MOV-10, Moloney leukemia virus 10 protein
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Primary Accession	Q9HCE1
Antigen Type	Synthetic Peptide
Application	WB, IHC-P
Bio Background	Probable RNA helicase. Required for RNA-mediated gene silencing by the RNA-induced silencing complex (RISC). Required for both miRNA-mediated translational repression and miRNA-mediated cleavage of complementary mRNAs by RISC. Also required for RNA-directed transcription and replication of the human hapatitis delta virus (HDV). Interacts with small capped HDV RNAs derived from genomic hairpin structures that mark the initiation sites of RNA-dependent HDV RNA transcription.
Bio References	El Messaoudi-Aubert, S., et al. Nat. Struct. Mol. Biol. 17(7):862-868(2010) Furtak, V., et al. PLoS ONE 5 (2), E9081 (2010) : Nakano, M., et al. Biochem. Biophys. Res. Commun. 388(2):328-332(2009) Haussecker, D., et al. Nat. Struct. Mol. Biol. 15(7):714-721(2008) Matsuoka, S., et al. Science 316(5828):1160-1166(2007)
Clonality	Polyclonal
Clone/Animal Names	RB35508
Gene ID	4343
Gene Name	MOV10 (HGNC:7200)
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	MOV10 Antibody (N-term) (Cat. #AP14933a) western blot analysis in human normal Uterus tissue lysates (35ug/lane).This demonstrates the MOV10 antibody detected the MOV10 protein (arrow).
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	All lanes : Anti-MOV10 Antibody (N-term) at 1:1000 dilution Lane 1: 293 whole cell lysate Lane 2: Hela whole cell lysate Lane 3: HepG2 whole cell lysate Lane 4: Jurkat whole cell lysate Lane 5: NIH/3T3 whole cell lysate Lane 6: F9 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 114 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Type image 2	WB
Dilution image 2	1:1000
Legend image 3	MOV10 Antibody (N-term) (AP14933a)immunohistochemistry analysis in formalin fixed and paraffin embedded human heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MOV10 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Type image 3	IHC-P
Dilution image 3	1:10~50
Other Accession	NP_001123551.1; NP_066014.1
Isotype	Rabbit Ig
Calculated MW	113671
Antigen Region	260-288
Antigen Source	HUMAN
Target/Specificity	This MOV10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 260-288 amino acids from the N-terminal region of human MOV10.
NCBI Accession	NP_001123551.1; NP_066014.1

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Menge: 80 ul

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Lieferung vsl. bis 02.10.2025

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