STAT2 Antibody (C-term)

Primary Antibodies; Signal Transduction; Antiviral defense; Host-virus interaction; Immune system process; Chemokine signaling; Interleukin signaling; JAK-STAT signaling; Jak-STAT signaling KEGG

STAT2 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P3/CBP (EP3/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus.

RB0311

Purified Rabbit Polyclonal Antibody (Pab)

97916

820-851

WB: 1:1000
IHC-P: 1:50~100