URM1 Antibody (N-term)

Synthetic Peptide

Following the discovery of protein modification by the small, highly conserved ubiquitin polypeptide, a number of distinct ubiquitin-like proteins (Ubls) have been found to function as protein modifiers as well. These Ubls, which include SUMO, ISG15, Nedd8, and Atg8, function as critical regulators of many cellular processes, including transcription, DNA repair, signal transduction, autophagy, and cell-cycle control. A growing body of data also implicates the dysregulation of Ubl-substrate modification and mutations in the Ubl-conjugation machinery in the etiology and progression of a number of human diseases. URM1 is a ubiquitin-like modifier protein.

Polyclonal

81605

Purified Rabbit Polyclonal Antibody (Pab)

Western blot analysis of hURM1 (arrow) using rabbit polyclonal hURM1 Antibody (N-term) (Cat.#AP1601a). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the hURM1 gene (Lane 2) (Origene Technologies).

1:1000

IHC-P

Rabbit Ig

8-40

This URM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 8-40 amino acids from the N-terminal region of human URM1.