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KRAS Antibody (C-term)

KRAS Antibody (C-term)

ArtNr	ABC-AP16356b-ev
Hersteller	Abcepta
Menge	50 ul
Kategorie	Oncology Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Cell Biology Adenocarcinoma Cytoskeleton Flow Cytometry Western Blot Immunofluorescence Primary Antibodies By Organ Lung Cancer Colorectal Cancer small GTPases Ras Subfamily
Typ	Antibody Polyclonal
Applikationen	WB, FC, IF
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Citations	Bruckman, K.C., et al. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 110(5):632-637(2010) Wong, K.K., et al. Am. J. Pathol. 177(4):1611-1617(2010) Irahara, N., et al. Diagn. Mol. Pathol. 19(3):157-163(2010) Carotenuto, P., et al. Pharmacogenomics 11(8):1169-1179(2010) Leventopoulos, G., et al. Clin. Exp. Rheumatol. 28(4):556-557(2010)
NCBI	NP_004976.2,NP_203524.1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GTPase KRas,K-Ras 2,Ki-Ras,c-K-ras,c-Ki-ras,GTPase KRas,N-terminally processed,KRAS,KRAS2,RASK2
Similar products	KRAS, N-terminally processed, KRAS2, RASK2, GTPase KRas, K-Ras 2, Ki-Ras, c-K-ras, c-Ki-ras
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Manufacturer - Category	Primary Antibodies; Cancer; Signal Transduction; Catalog Updated; B cell receptor signaling; T cell receptor signaling; Chemokine signaling; Inflammation mediated by chemokine and cytokine signaling
Manufacturer - Targets	This KRAS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 146-174 amino acids from the C-terminal region of human KRAS.
Bio Background	This gene, a Kirsten ras oncogene homolog from themammalian ras gene family, encodes a protein that is a member ofthe small GTPase superfamily. A single amino acid substitution isresponsible for an activating mutation. The transforming proteinthat results is implicated in various malignancies, including lungadenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreasand colorectal carcinoma. Alternative splicing leads to variantsencoding two isoforms that differ in the C-terminal region.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB32708
Gene Name	KRAS
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H, M, Rat
Predicted Reactivity	Rat
Calculated Molecular Weight	21656
Antigen Source	HUMAN
Antigen Region	146-174
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	IF: 1:10~50 WB: 1:2000 WB: 1:500 WB: 1:2000 FC: 1:10~50
Antigen Type	Synthetic Peptide

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 50 ul

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