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SIAH1 Antibody (Center)

SIAH1 Antibody (Center)

ArtNr	ABC-AP16396c
Hersteller	Abcepta
Menge	400 ul
Kategorie	Oncology Antibodies Western Blot Primary Antibodies By Organ Colorectal Cancer
Typ	Antibody Polyclonal
Applikationen	WB
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Wu, H., et al. Biochem. Biophys. Res. Commun. 397(3):391-396(2010) Wen, Y.Y., et al. Mol. Carcinog. 49(5):440-449(2010) Dimitrova, Y.N., et al. J. Biol. Chem. 285(18):13507-13516(2010) Bruzzoni-Giovanelli, H., et al. J. Exp. Clin. Cancer Res. 29, 10 (2010): Xie, W., et al. J. Cell. Mol. Med. 13 (8B), 1719-1727 (2009) :
NCBI	NP_001006611.1,NP_003022.3
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	E3 ubiquitin-protein ligase SIAH1,632-,Seven in absentia homolog 1,Siah-1,Siah-1a,SIAH1,HUMSIAH
Similar products	SIAH1, HUMSIAH, E3 ubiquitin-protein ligase SIAH1, Seven in absentia homolog 1, Siah-1a, Siah-1, 632-
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Manufacturer - Category	Primary Antibodies; Cell Biology; Neuroscience; Anti-Wnt-Pathway (plus Lgr5) Antibodies
Manufacturer - Targets	This SIAH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 92-120 amino acids from the Central region of human SIAH1.
Bio Background	SIAH1 is a protein that is a member of the sevenin absentia homolog (SIAH) family. The protein is an E3 ligase andis involved in ubiquitination and proteasome-mediated degradationof specific proteins. The activity of this ubiquitin ligase hasbeen implicated in the development of certain forms of Parkinson'sdisease, the regulation of the cellular response to hypoxia andinduction of apoptosis. Alternative splicing results in severaladditional transcript variants, some encoding different isoformsand others that have not been fully characterized. [provided byRefSeq].
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB35749
Gene Name	SIAH1
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Calculated Molecular Weight	31123
Antigen Source	HUMAN
Antigen Region	92-120
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	WB: 1:1000
Antigen Type	Synthetic Peptide

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Menge: 400 ul

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