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ATF3 Antibody (C-term)

ATF3 Antibody (C-term)

ArtNr	ABC-AP16577b-ev
Hersteller	Abcepta
Menge	80 ul
Kategorie	Neuroscience Targets for Rodent Neurosciences Aging & Neurological Disorders Neural Signaling Antibodies Flow Cytometry Western Blot Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	WB, FC
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Lee, S.H., et al. Oncogene 29(37):5182-5192(2010) Park, H.J., et al. Biochem. Biophys. Res. Commun. 400(1):72-77(2010) Wu, X., et al. Nature 465(7296):368-372(2010) Koh, I.U., et al. FEBS J. 277(10):2304-2317(2010)
NCBI	NP_001025458.1,NP_001035709.1,NP_001193413.2,NP_001193415.1,NP_001193417.2,NP_001665.1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Cyclic AMP-dependent transcription factor ATF-3,cAMP-dependent transcription factor ATF-3,Activating transcription factor 3,ATF3
Similar products	ATF3, Cyclic AMP-dependent transcription factor ATF-3, Activating transcription factor 3, cAMP-dependent transcription factor ATF-3
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Manufacturer - Category	Primary Antibodies; Cancer; Apoptosis signaling
Manufacturer - Targets	This ATF3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 140-168 amino acids from the C-terminal region of human ATF3.
Bio Background	Activating transcription factor 3 is a member of themammalian activation transcription factor/cAMP responsiveelement-binding (CREB) protein family of transcription factors.Multiple transcript variants encoding two different isoforms havebeen found for this gene. The longer isoform represses rather thanactivates transcription from promoters with ATF binding elements.The shorter isoform (deltaZip2) lacks the leucine zipperprotein-dimerization motif and does not bind to DNA, and itstimulates transcription presumably by sequestering inhibitoryco-factors away from the promoter. It is possible that alternativesplicing of the ATF3 gene may be physiologically important in theregulation of target genes.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB30340
Gene Name	ATF3 {ECO:0000303\|PubMed:7515060, ECO:0000312\|HGNC:HGNC:785}
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Predicted Reactivity	B, M, Rat
Calculated Molecular Weight	20576
Antigen Source	HUMAN
Antigen Region	140-168
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	WB: 1:1000 WB: 1:1000 FC: 1:10~50
Antigen Type	Synthetic Peptide

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 80 ul

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