Bio Background |
The protein encoded by this gene, a member of thecarnitine/choline acetyltransferase family, is the rate-controllingenzyme of the long-chain fatty acid beta-oxidation pathway inmuscle mitochondria. This enzyme is required for the net transportof long-chain fatty acyl-CoAs from the cytoplasm into themitochondria. Multiple transcript variants encoding differentisoforms have been found for this gene, and read-throughtranscripts are expressed from the upstream locus that includeexons from this gene. |
Bio References |
Matsuo, T., et al. Biochem. Genet. 48 (3-4), 193-201 (2010) :Miljkovic, I., et al. Obesity (Silver Spring) 17(7):1396-1401(2009)Miyagawa, T., et al. PLoS ONE 4 (4), E5394 (2009) :van der Leij, F.R., et al. J. Biol. Chem. 277(30):26994-27005(2002)Yamazaki, N., et al. J. Biol. Chem. 275(41):31739-31746(2000) |