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PTPN22 Antibody (C-term)

ArtNr ABC-AP16722B-ev
Hersteller Abcepta
Menge 80 ul
Kategorie
Typ Antibody Polyclonal
Applikationen WB
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Citations Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Andersen, M.K., et al. Diabetes Care 33(9):2062-2064(2010)
Bianco, B., et al. Scand. J. Immunol. 72(3):256-259(2010)
Pradhan, V., et al. J Postgrad Med 56(3):239-242(2010)
Sfar, I., et al. Arch Inst Pasteur Tunis 86 (1-4), 51-62 (2009) :
NCBI NP_001180360.1,NP_036543.4,NP_057051.3
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Tyrosine-protein phosphatase non-receptor type 22,Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP,Lymphoid phosphatase,LyP,PEST-domain phosphatase,PEP,PTPN22,PTPN8
Similar products PTPN22, PTPN8, Tyrosine-protein phosphatase non-receptor type 22, Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP, Lymphoid phosphatase, PEST-domain phosphatase, PEP, LyP
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Manufacturer - Category
Primary Antibodies; Signal Transduction; Catalog Updated; Immunity; Autophagy
Manufacturer - Targets
This PTPN22 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 663-691 amino acids from the C-terminal region of human PTPN22.
Bio Background
This gene encodes of member of the non-receptor class 4subfamily of the protein-tyrosine phosphatase family. The encodedprotein is a lymphoid-specific intracellular phosphatase thatassociates with the molecular adapter protein CBL and may beinvolved in regulating CBL function in the T-cell receptorsignaling pathway. Mutations in this gene may be associated with arange of autoimmune disorders including Type 1 Diabetes, rheumatoidarthritis, systemic lupus erythematosus and Graves' disease.Alternatively spliced transcript variants encoding distinctisoforms have been described.
Clonality
Polyclonal
Polyclonal Antibody Additonal Information
RB36243
Gene Name
PTPN22
Subtitle
Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H
Calculated Molecular Weight
91705
Antigen Source
HUMAN
Antigen Region
663-691
Formulation
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution
WB: 1:1000
Antigen Type
Synthetic Peptide

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 80 ul
Lieferbar: In stock
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