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PTPRN2 Antibody (N-term)

ArtNr ABC-AP16733a
Hersteller Abcepta
Menge 400 ul
Kategorie
Typ Antibody Polyclonal
Applikationen WB
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Citations Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010):
Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34(5):800-812(2010)
Yoshida, T., et al. Int. J. Mol. Med. 25(4):649-656(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
NCBI NP_002838.2,NP_570857.2,NP_570858.2
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Receptor-type tyrosine-protein phosphatase N2,R-PTP-N2,Islet cell autoantigen-related protein,IAR,ICAAR,Phogrin,PTPRN2,KIAA0387
Similar products PTPRN2, KIAA0387, Receptor-type tyrosine-protein phosphatase N2, Islet cell autoantigen-related protein, Phogrin, IAR, ICAAR, R-PTP-N2
Lieferbar
Manufacturer - Category
Primary Antibodies; Immunology; Signal Transduction
Manufacturer - Targets
This PTPRN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 161-189 amino acids from the N-terminal region of human PTPRN2.
Bio Background
The protein encoded by this gene is a member of theprotein tyrosine phosphatase (PTP) family. PTPs are known to besignaling molecules that regulate a variety of cellular processesincluding cell growth, differentiation, mitotic cycle, andoncogenic transformation. This PTP possesses an extracellularregion, a single transmembrane region, and a single intracellularcatalytic domain, and thus represents a receptor-type PTP. Thecatalytic domain of this PTP is most closely related toPTPRN/IA-2beta. This PTP and PTPRN are both found to be majorautoantigens associated with insulin-dependent diabetes mellitus.Three alternatively spliced transcript variants of this gene, whichencode distinct proteins, have been reported.
Clonality
Polyclonal
Polyclonal Antibody Additonal Information
RB36264
Gene Name
PTPRN2
Subtitle
Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H
Calculated Molecular Weight
111271
Antigen Source
HUMAN
Antigen Region
161-189
Formulation
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution
WB: 1:1000
Antigen Type
Synthetic Peptide

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 400 ul
Lieferbar: In stock
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