ATF2 Antibody (Center T339)

Crown Antibodies; Primary Antibodies; Immunology; Apoptosis signaling; Mitochondrion; Mitochondrion outer membrane

This gene encodes a transcription factor that is a memberof the leucine zipper family of DNA binding proteins. This proteinbinds to the cAMP-responsive element (CRE), an octamericpalindrome. The protein forms a homodimer or heterodimer with c-Junand stimulates CRE-dependent transcription. The protein is also ahistone acetyltransferase (HAT) that specifically acetylateshistones H2B and H4 in vitro; thus it may represent a class ofsequence-specific factors that activate transcription by directeffects on chromatin components. Additional transcript variantshave been identified but their biological validity has not beendetermined.

RB36858

Affinity Purified Rabbit Polyclonal Antibody (Pab)

54537

318-347

WB: 1:1000

Cyclic AMP-dependent transcription factor ATF-2, cAMP-dependent transcription factor ATF-2, Activating transcription factor 2, Cyclic AMP-responsive element-binding protein 2, CREB-2, cAMP-responsive element-binding protein 2, HB16, Histone acetyltransferase ATF2, cAMP response element-binding protein CRE-BP1, ATF2, CREB2, CREBP1