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HDAC1 Antibody (Center S423)

HDAC1 Antibody (Center S423)

ArtNr	ABC-AP16867c
Hersteller	Abcepta
Menge	400 ul
Kategorie	Oncology Neuroscience Aging & Neurological Disorders Neural Epigenetics Antibodies By Cell Type Carcinoma Hematology Lymphoma Melanoma Sarcoma Western Blot Immunofluorescence Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	WB, IF
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Citations	Yang, Z., et al. Clin. Chem. Lab. Med. 48(12):1785-1791(2010) Grausenburger, R., et al. J. Immunol. 185(6):3489-3497(2010) Miller, K.M., et al. Nat. Struct. Mol. Biol. 17(9):1144-1151(2010) Brandt, S., et al. Int. J. Biochem. Cell Biol. 42(9):1472-1481(2010) Leone, V., et al. Oncogene 29(30):4341-4351(2010)
NCBI	NP_004955.2
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Histone deacetylase 1,HD1,HDAC1,RPD3L1
Similar products	HDAC1, HD1, RPD3L1, Histone deacetylase 1
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Manufacturer - Category	Crown Antibodies; Primary Antibodies; Cardiovascular; Cell Biology; Signal Transduction; Anti-Wnt-Pathway (plus Lgr5) Antibodies; Viral process; Host-virus interaction
Manufacturer - Targets	This HDAC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 402-430 amino acids from the Central region of human HDAC1.
Bio Background	Histone acetylation and deacetylation, catalyzed bymultisubunit complexes, play a key role in the regulation ofeukaryotic gene expression. The protein encoded by this genebelongs to the histone deacetylase/acuc/apha family and is acomponent of the histone deacetylase complex. It also interactswith retinoblastoma tumor-suppressor protein and this complex is akey element in the control of cell proliferation anddifferentiation. Together with metastasis-associated protein-2, itdeacetylates p53 and modulates its effect on cell growth andapoptosis.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB36865
Gene Name	HDAC1 {ECO:0000303\|PubMed:10846170, ECO:0000312\|HGNC:HGNC:4852}
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H, M, Rat
Calculated Molecular Weight	55103
Antigen Source	HUMAN
Antigen Region	402-430
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	IF: 1:10~50 WB: 1:1000
Antigen Type	Synthetic Peptide

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Menge: 400 ul

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