PRKAG3 Antibody (C-term)

Crown Antibodies; Primary Antibodies; Cancer; Cardiovascular; Metabolism; Signal Transduction

The protein encoded by this gene is a regulatory subunitof the AMP-activated protein kinase (AMPK). AMPK is a heterotrimerconsisting of an alpha catalytic subunit, and non-catalytic betaand gamma subunits. AMPK is an important energy-sensing enzyme thatmonitors cellular energy status. In response to cellular metabolicstresses, AMPK is activated, and thus phosphorylates andinactivates acetyl-CoA carboxylase (ACC) and beta-hydroxybeta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved inregulating de novo biosynthesis of fatty acid and cholesterol. Thissubunit is one of the gamma regulatory subunits of AMPK. It isdominantly expressed in skeletal muscle. Studies of the pigcounterpart suggest that this subunit may play a key role in theregulation of energy metabolism in skeletal muscle. [provided byRefSeq].

RB30387

Affinity Purified Rabbit Polyclonal Antibody (Pab)

B, M

HUMAN

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Synthetic Peptide