KCNA5 Antibody (C-term)

Primary Antibodies; Cancer; Cardiovascular; Metabolism; Neuroscience

Potassium channels represent the most complex class ofvoltage-gated ino channels from both functional and structuralstandpoints. Their diverse functions include regulatingneurotransmitter release, heart rate, insulin secretion, neuronalexcitability, epithelial electrolyte transport, smooth musclecontraction, and cell volume. Four sequence-related potassiumchannel genes - shaker, shaw, shab, and shal - have been identifiedin Drosophila, and each has been shown to have human homolog(s).This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains sixmembrane-spanning domains with a shaker-type repeat in the fourthsegment. It belongs to the delayed rectifier class, the function ofwhich could restore the resting membrane potential of beta cellsafter depolarization and thereby contribute to the regulation ofinsulin secretion. This gene is intronless, and the gene isclustered with genes KCNA1 and KCNA6 on chromosome 12. [provided byRefSeq].

RB36837

Affinity Purified Rabbit Polyclonal Antibody (Pab)

67228

508-536

WB: 1:1000