NR3C2 Antibody (Center)

Primary Antibodies; Cardiovascular; Signal Transduction

This gene encodes the mineralocorticoid receptor, whichmediates aldosterone actions on salt and water balance withinrestricted target cells. The protein functions as aligand-dependent transcription factor that binds tomineralocorticoid response elements in order to transactivatetarget genes. Mutations in this gene cause autosomal dominantpseudohypoaldosteronism type I, a disorder characterized by urinarysalt wasting. Defects in this gene are also associated with earlyonset hypertension with severe exacerbation in pregnancy.Alternative splicing results in multiple transcript variants.

RB36767

Affinity Purified Rabbit Polyclonal Antibody (Pab)

M, Rat, X

HUMAN

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Synthetic Peptide