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CD68/CD68 (kpi) Antibody (Center)

CD68/CD68 (kpi) Antibody (Center)

ArtNr	ABC-AP17393C
Hersteller	Abcepta
Menge	400 ul
Kategorie	Neuroscience Neural Lineage Markers Antibodies Western Blot Primary Antibodies Calcium Binding Protein Markers
Typ	Antibody Polyclonal
Applikationen	WB
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Leonarduzzi, G., et al. Mol Nutr Food Res 54 SUPPL 1, S31-S41 (2010): Strojnik, T., et al. Anticancer Res. 29(8):3269-3279(2009) Sayed, S., et al. Eur J Vasc Endovasc Surg 38(1):20-25(2009) Suzuki, Y., et al. Int J Rheum Dis 12(1):7-13(2009) Chen, W.S., et al. Scand. J. Rheumatol. 38(2):154-155(2009)
NCBI	NP_001035148.1,NP_001242.2
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Macrosialin,Gp110,CD68,CD68
Similar products	CD68, Macrosialin, Gp110
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Manufacturer - Category	Primary Antibodies; Immunology; Lysosome
Manufacturer - Targets	This CD68/CD68 (kpi) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 209-237 amino acids from the Central region of human CD68/CD68 (kpi).
Bio Background	This gene encodes a 11-kD transmembrane glycoprotein thatis highly expressed by human monocytes and tissue macrophages. Itis a member of the lysosomal/endosomal-associated membraneglycoprotein (LAMP) family. The protein primarily localizes tolysosomes and endosomes with a smaller fraction circulating to thecell surface. It is a type I integral membrane protein with aheavily glycosylated extracellular domain and binds to tissue- andorgan-specific lectins or selectins. The protein is also a memberof the scavenger receptor family. Scavenger receptors typicallyfunction to clear cellular debris, promote phagocytosis, andmediate the recruitment and activation of macrophages. Alternativesplicing results in multiple transcripts encoding differentisoforms.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB36354
Gene Name	CD68
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Calculated Molecular Weight	37408
Antigen Source	HUMAN
Antigen Region	209-237
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	WB: 1:1000
Antigen Type	Synthetic Peptide

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 400 ul

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