CD68/CD68 (kpi) Antibody (Center)

Synthetic Peptide

This gene encodes a 110-kD transmembrane glycoprotein that
is highly expressed by human monocytes and tissue macrophages. It
is a member of the lysosomal/endosomal-associated membrane
glycoprotein (LAMP) family. The protein primarily localizes to
lysosomes and endosomes with a smaller fraction circulating to the
cell surface. It is a type I integral membrane protein with a
heavily glycosylated extracellular domain and binds to tissue- and
organ-specific lectins or selectins. The protein is also a member
of the scavenger receptor family. Scavenger receptors typically
function to clear cellular debris, promote phagocytosis, and
mediate the recruitment and activation of macrophages. Alternative
splicing results in multiple transcripts encoding different
isoforms.

Polyclonal

968

Affinity Purified Rabbit Polyclonal Antibody (Pab)

CD68/CD68 (kpi) Antibody (Center) (Cat. #AP17393c) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the CD68/CD68 (kpi) antibody detected the CD68/CD68 (kpi) protein (arrow).

1:1000

Rabbit Ig

209-237

This CD68/CD68 (kpi) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 209-237 amino acids from the Central region of human CD68/CD68 (kpi).