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FANCA Antibody (Center)

FANCA Antibody (Center)

ArtNr	ABC-AP18008C
Hersteller	Abcepta
Menge	400 ul
Kategorie	Oncology Metabolism Glucose Homeostasis Cholesterol & Lipid Metabolism Antibodies By Cell Type Blastoma Carcinoma Hematology Lymphoma Myeloma Melanoma Sarcoma Western Blot Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	WB
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010) Monsees, G.M., et al. Breast Cancer Res. Treat. (2010) In press: Eriksson, N., et al. PLoS Genet. 6 (6), E1000993 (2010): Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
NCBI	NP_000126.2,NP_001018122.1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Fanconi anemia group A protein,Protein FACA,FANCA,FAA,FACA,FANCH
Similar products	FANCA, FAA, FACA, FANCH, Fanconi anemia group A protein, Protein FACA
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Manufacturer - Category	Primary Antibodies
Manufacturer - Targets	This FANCA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 667-694 amino acids from the Central region of human FANCA.
Bio Background	The Fanconi anemia complementation group (FANC) currentlyincludes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCMand FANCN (also called PALB2). The previously defined group FANCHis the same as FANCA. Fanconi anemia is a genetically heterogeneousrecessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomalbreakage, and defective DNA repair. The members of the Fanconianemia complementation group do not share sequence similarity; theyare related by their assembly into a common nuclear proteincomplex. This gene encodes the protein for complementation group A.Alternative splicing results in multiple transcript variantsencoding different isoforms. Mutations in this gene are the mostcommon cause of Fanconi anemia.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB23899
Gene Name	FANCA
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Calculated Molecular Weight	162775
Antigen Source	HUMAN
Antigen Region	667-694
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	WB: 1:1000
Antigen Type	Synthetic Peptide

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