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ATG9A Antibody (C-term)

ATG9A Antibody (C-term)

ArtNr	ABC-AP1814C
Hersteller	Abcepta
Menge	400 ul
Kategorie	Antibodies Immunohistochemistry Western Blot Immunofluorescence Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	WB, IF, IHC-P
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	References for protein: 1.Baehrecke EH. Nat Rev Mol Cell Biol. 6(6):505-10. (2005) 2.Lum JJ, et al. Nat Rev Mol Cell Biol. 6(6):439-48. (2005) 3.Greenberg JT. Dev Cell. 8(6):799-801. (2005) 4.Levine B. Cell. 120(2):159-62. (2005) 5.Shintani T and Klionsky DJ. Science. 306(5698):990-5. (2004) References for U251 cell line: 1. Westermark B.; Pontén J.; Hugosson R. (1973).” Determinants for the establishment of permanent tissue culture lines from human gliomas”. Acta Pathol Microbiol Scand A. 81:791-805. [PMID: 4359449]. 2. Pontén, J.,Westermark B. (1978).” Properties of Human Malignant Glioma Cells in Vitro”. Medical Biology 56: 184-193.[PMID: 359950]. 3. Geng Y.;Kohli L.; Klocke B.J.; Roth K.A.(2010). “Chloroquine-induced autophagic vacuole accumulation and cell death in glioma cells is p53 independent”. Neuro Oncol. 12(5): 473–481.[ PMID: 20406898].
NCBI	NP_001070666.1,NP_076990.4
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Autophagy-related protein 9A,APG9-like 1,mATG9,ATG9A,APG9L1
Similar products	ATG9A, APG9L1, Autophagy-related protein 9A, APG9-like 1, mATG9
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Manufacturer - Category	Primary Antibodies; Antibody Collections; Cancer; Cardiovascular; Cell Biology; Metabolism; Neuroscience; Signal Transduction; Autophagy; Autophagy
Manufacturer - Targets	This ATG9A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 717-746 amino acids from the C-terminal region of human ATG9A.
Bio Background	Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). Apg9 plays a direct role in the formation of the cytoplasm to vacuole targeting and autophagic vesicles, possibly serving as a marker for a specialized compartment essential for these vesicle-mediated alternative targeting pathways.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB7505, RB7506
Gene Name	ATG9A {ECO:0000303\|PubMed:20124090, ECO:0000312\|HGNC:HGNC:22408}
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Calculated Molecular Weight	94447
Antigen Source	HUMAN
Antigen Region	717-746
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Dilution	IF: 1:100 WB: 1:1000 WB: 1:1000 IHC-P: 1:50~100
Antigen Type	Synthetic Peptide

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Menge: 400 ul

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