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ATG10 Antibody (N-term)

ATG10 Antibody (N-term)

ArtNr	ABC-AP1815a-ev
Hersteller	Abcepta
Menge	80 ul
Kategorie	Antibodies Cell Biology Cell Status Immunohistochemistry Autophagy Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	IHC-P
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Baehrecke EH. Nat Rev Mol Cell Biol. 6(6):505-10. (2005) Lum JJ, et al. Nat Rev Mol Cell Biol. 6(6):439-48. (2005) Greenberg JT. Dev Cell. 8(6):799-801. (2005) Levine B. Cell. 120(2):159-62. (2005) Shintani T and Klionsky DJ. Science. 306(5698):990-5. (2004)
NCBI	NP_001124500.1,NP_113670.1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Ubiquitin-like-conjugating enzyme ATG10,632-,Autophagy-related protein 10,APG10-like,ATG10,APG10L
Similar products	ATG10, Ubiquitin-like-conjugating enzyme ATG10, Autophagy-related protein 10, APG10-like, APG10L, 632-
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Manufacturer - Category	Primary Antibodies; Cancer; Cardiovascular; Cell Biology; Metabolism; Neuroscience; Autophagy; Regulation of autophagy
Manufacturer - Targets	This ATG10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15~45 amino acids from the N-term of human APG10L.
Bio Background	Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). APG1 is an ATG12-conjugating enzyme (E2-like enzyme) that likely serves as an ATG5-recognition molecule. This protein interacts with MAP1LC3A. By interacting with MAP1LC3A, it plays a role in the conjugation of ATG12 to ATG5. APG1 also is able to directly interact either with ATG5 or ATG7.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB7550
Gene Name	ATG10
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Calculated Molecular Weight	25279
Antigen Source	HUMAN
Antigen Region	15-45
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Dilution	IHC-P: 1:50~100
Antigen Type	Synthetic Peptide

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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