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EGF Antibody (C-term)

ArtNr ABC-AP19126b-ev
Hersteller Abcepta
Menge 80 ul
Kategorie
Typ Antibody Polyclonal
Applikationen WB
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Citations de Diesbach, M.T., et al. Exp. Cell Res. 316(19):3239-3253(2010)
Xu, Z., et al. Biochem. Biophys. Res. Commun. 401(3):376-381(2010)
Lupien, M., et al. Genes Dev. 24(19):2219-2227(2010)
Hommel, U., et al. J. Mol. Biol. 227(1):271-282(1992)
Hernandez-Sotomayor, S.M., et al. J. Membr. Biol. 128(2):81-89(1992)
NCBI NP_001171601.1,NP_001171602.1,NP_001954.2
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Pro-epidermal growth factor,EGF,Epidermal growth factor,Urogastrone,EGF
Similar products EGF, Pro-epidermal growth factor, Epidermal growth factor, Urogastrone
Lieferbar
Manufacturer - Category
Primary Antibodies; Cancer; Cell Biology; Signal Transduction
Manufacturer - Targets
This EGF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 940-967 amino acids from the C-terminal region of human EGF.
Bio Background
This gene encodes a member of the epidermal growth factorsuperfamily. The encoded protein is synthesized as a largeprecursor molecule that is proteolytically cleaved to generate the53-amino acid epidermal growth factor peptide. This protein acts apotent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. Thisprotein acts by binding the high affinity cell surface receptor, epidermal growth factor receptor. Defects in this gene are thecause of hypomagnesemia type 4. Dysregulation of this gene has beenassociated with the growth and progression of certain cancers.Alternate splicing results in multiple transcript variants.
Clonality
Polyclonal
Polyclonal Antibody Additonal Information
RB30519
Gene Name
EGF
Subtitle
Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H
Calculated Molecular Weight
133994
Antigen Source
HUMAN
Antigen Region
940-967
Formulation
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution
WB: 1:1000
Antigen Type
Synthetic Peptide

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 80 ul
Lieferbar: In stock
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