Vergleich

CCNDBP1 Antibody(N-term)

ArtNr ABC-AP19416a-ev-80ul
Hersteller Abcepta
Menge 80 ul
Kategorie
Typ Antibody Polyclonal
Applikationen Western Blot
Specific against other
Host Rabbit
Isotype Ig
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Cyclin-D1-binding protein 1, Grap2 and cyclin-D-interacting protein, Human homolog of Maid, CCNDBP1, DIP1, GCIP, HHM
Lieferbar
Primary Accession
O95273
Other Accession
Q4R809; NP_036274.3
Antigen Type
Synthetic Peptide
Bio Background
This gene was identified by the interaction of its gene
product with Grap2, a leukocyte-specific adaptor protein important
for immune cell signaling. The protein encoded by this gene was
shown to interact with cyclin D. Transfection of this gene in cells
was reported to reduce the phosphorylation of Rb gene product by
cyclin D-dependent protein kinase, and inhibit E2F1-mediated
transcription activity. This protein was also found to interact
with helix-loop-helix protein E12 and is thought to be a negative
regulator of liver-specific gene expression. Several alternatively
spliced variants have been found for this gene. [provided by
RefSeq].
Bio References
Lee, I., et al. Cancer Res. 70(11):4357-4365(2010)
Seto, A., et al. Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 65 (PT 1), 21-24 (2009) :
Ikushima, H., et al. EMBO J. 27(22):2955-2965(2008)
Chen, W.C., et al. Histopathology 53(5):554-560(2008)
Chang, T.W., et al. Oncogene 27(3):332-338(2008)
Gene ID
23582
Gene Name
CCNDBP1
Reactivity
H
Predicted
Pr
Calculated MW
40262
Antigen Region
21-49
Antigen Source
HUMAN
Target/Specificity
This CCNDBP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-49 amino acids from the N-terminal region of human CCNDBP1.
NCBI Accession
NP_036274.3

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