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FANCL Antibody(C-term)

FANCL Antibody(C-term)

ArtNr	ABC-AP19508b
Hersteller	Abcepta
Menge	400 ul
Kategorie	Oncology Antibodies By Cell Type Blastoma Carcinoma Hematology Lymphoma Myeloma Melanoma Sarcoma Western Blot Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	WB
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Zhang, J., et al. J. Clin. Invest. 120(5):1524-1534(2010) Garcia, M.J., et al. Carcinogenesis 30(11):1898-1902(2009) McWilliams, R.R., et al. Cancer Epidemiol. Biomarkers Prev. 18(9):2549-2552(2009) Longerich, S., et al. J. Biol. Chem. 284(35):23182-23186(2009) Hess, C.J., et al. Cell. Oncol. 30(4):299-306(2008)
NCBI	NP_001108108.1,NP_060532.2
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	E3 ubiquitin-protein ligase FANCL,632-,Fanconi anemia group L protein,Fanconi anemia-associated polypeptide of 43 kDa,FAAP43,FANCL,PHF9
Similar products	FANCL, PHF9, E3 ubiquitin-protein ligase FANCL, Fanconi anemia group L protein, Fanconi anemia-associated polypeptide of 43 kDa, FAAP43, 632-
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Manufacturer - Category	Primary Antibodies
Manufacturer - Targets	This FANCL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 274-302 amino acids from the C-terminal region of human FANCL.
Bio Background	The Fanconi anemia complementation group (FANC) currentlyincludes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCMand FANCN (also called PALB2). The previously defined group FANCHis the same as FANCA. Fanconi anemia is a genetically heterogeneousrecessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomalbreakage, and defective DNA repair. The members of the Fanconianemia complementation group do not share sequence similarity; theyare related by their assembly into a common nuclear proteincomplex. This gene encodes the protein for complementation group L.Alternative splicing results in two transcript variants encodingdifferent isoforms.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB23901
Gene Name	FANCL
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Calculated Molecular Weight	42905
Antigen Source	HUMAN
Antigen Region	274-302
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	WB: 1:1000
Antigen Type	Synthetic Peptide

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