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CTNNB1 Antibody(C-term)

CTNNB1 Antibody(C-term)

ArtNr	ABC-AP19559b-ev
Hersteller	Abcepta
Menge	80 ul
Kategorie	Oncology Neuroscience Neural Adhesion Molecules Antibodies By Cell Type Blastoma Carcinoma Hematology Leukemia Adenocarcinoma Western Blot Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	WB
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Huang, W., et al. Mol. Cell. Biol. 30(19):4575-4594(2010) Chairoungdua, A., et al. J. Cell Biol. 190(6):1079-1091(2010) Mirza, M.K., et al. J. Exp. Med. 207(8):1675-1685(2010) Guo, Q., et al. Acta Biochim. Biophys. Sin. (Shanghai) 42(7):450-456(2010) Teng, Y., et al. Zhonghua Yi Xue Za Zhi 90(14):988-992(2010)
NCBI	NP_001091679.1,NP_001091680.1,NP_001895.1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Catenin beta-1,Beta-catenin,CTNNB1,CTNNB
Similar products	Catenin beta-1, CTNNB1, CTNNB, Beta-catenin
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Manufacturer - Category	Primary Antibodies; Cancer; Cardiovascular; Neuroscience; Signal Transduction; Anti-Wnt-Pathway (plus Lgr5) Antibodies
Manufacturer - Targets	This CTNNB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 692-721 amino acids from the C-terminal region of human CTNNB1.
Bio Background	The protein encoded by this gene is part of a complex ofproteins that constitute adherens junctions (AJs). AJs arenecessary for the creation and maintenance of epithelial celllayers by regulating cell growth and adhesion between cells. Theencoded protein also anchors the actin cytoskeleton and may beresponsible for transmitting the contact inhibition signal thatcauses cells to stop dividing once the epithelial sheet iscomplete. Finally, this protein binds to the product of the APCgene, which is mutated in adenomatous polyposis of the colon.Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer.Three transcript variants encoding the same protein have been foundfor this gene.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB41124
Gene Name	CTNNB1
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Predicted Reactivity	B, Zf, M, Rat
Calculated Molecular Weight	85497
Antigen Source	HUMAN
Antigen Region	692-721
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	WB: 1:1000 WB: 1:1000
Antigen Type	Synthetic Peptide

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 80 ul

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Lieferung vsl. bis 05.03.2026

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