XPC Antibody(N-term)

Synthetic Peptide

This gene encodes a component of the nucleotide excision
repair (NER) pathway. There are multiple components involved in the
NER pathway, including Xeroderma pigmentosum (XP) A-G and V,
Cockayne syndrome (CS) A and B, and trichothiodystrophy (TTD) group
A, etc. This component, XPC, plays an important role in the early
steps of global genome NER, especially in damage recognition, open
complex formation, and repair protein complex formation. Mutations
in this gene or some other NER components result in Xeroderma
pigmentosum, a rare autosomal recessive disorder characterized by
increased sensitivity to sunlight with the development of
carcinomas at an early age. Alternatively spliced transcript
variants have been found for this gene.

Polyclonal

7508

Affinity Purified Rabbit Polyclonal Antibody (Pab)

All lanes : Anti-XPC Antibody (N-term) at 1:2000 dilution
Lane 1: Hela whole cell lysate
Lane 2: MCF-7 whole cell lysate
Lane 3: ZR-75-1 whole cell lysate

Lysates/proteins at 20 µg per lane.

Secondary
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.

Predicted band size : 106 kDa

Blocking/Dilution buffer: 5% NFDM/TBST.

1:2000

Rabbit Ig

154-183

This XPC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 154-183 amino acids from the N-terminal region of human XPC.