MMP26 Antibody (Center)

Primary Antibodies; Cancer; Cell Biology; Signal Transduction

Proteins of the matrix metalloproteinase (MMP) family areinvolved in the breakdown of extracellular matrix in normalphysiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in diseaseprocesses, such as arthritis and metastasis. Most MMP's aresecreted as inactive proproteins which are activated when cleavedby extracellular proteinases. The encoded protein degrades type IVcollagen, fibronectin, fibrinogen, casein, vitronectin, alpha1-antitrypsin, alpha 2-macroglobulin, and insulin-like growthfactor-binding protein 1, and activates MMP9 by cleavage. Theprotein differs from most MMP family members in that it lacks aconserved C-terminal protein domain.

RB41665

Affinity Purified Rabbit Polyclonal Antibody (Pab)

29708

96-125

WB: 1:1000