SOX2 Antibody (C265)

ArtNr	ABC-AP2048e
Hersteller	Abcepta
Menge	400 ul
Kategorie	Oncology Neuroscience Neural Lineage Markers Antibodies By Cell Type Carcinoma Flow Cytometry Western Blot Immunofluorescence Primary Antibodies Calcium Binding Protein Markers Interneuron Markers
Typ	Antibody Polyclonal
Applikationen	WB, FC, IF
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	References for protein: 1.Remenyi, A., et al., Genes Dev. 17(16):2048-2059 (2003). 2.Wiebe, M.S., et al., J. Biol. Chem. 278(20):17901-17911 (2003). 3.Fantes, J., et al., Nat. Genet. 33(4):461-463 (2003). 4.Schepers, G.E., et al., Dev. Cell 3(2):167-170 (2002). 5.Kamachi, Y., et al., Trends Genet. 16(4):182-187 (2000). References for SY5Y (SH-SY5Y; ATCC#CRL-2266): 1. Ross RA, et al. Coordinate morphological and biochemical interconversion of human neuroblastoma cells. J. Natl. Cancer Inst. 71: 741-749, 1983. [PubMed: 6137586]; 2. Biedler JL, et al. Multiple neurotransmitter synthesis by human neuroblastoma cell lines and clones. Cancer Res. 38: 3751-3757, 1978. [PubMed: 29704].
NCBI	NP_003097.1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Transcription factor SOX-2,SOX2
Similar products	SOX2, Transcription factor SOX-2
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Manufacturer - Category	Primary Antibodies; Developmental Biology; Neuroscience; Signal Transduction
Manufacturer - Targets	This SOX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 251-284 amino acids from human SOX2.
Bio Background	SOX2 is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. This protein may act as a transcriptional activator after forming a protein complex with other proteins. Mutations in the SOX2 gene have been associated with bilateral anophthalmia, a severe form of structural eye malformation.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB14259
Gene Name	SOX2
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Predicted Reactivity	C, M, Sh, X
Calculated Molecular Weight	34310
Antigen Source	HUMAN
Antigen Region	251-284
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Dilution	IF: 1:100 WB: 1:1000 WB: 1:1000 FC: 1:10~50
Antigen Type	Synthetic Peptide

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