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(Mouse) Smad2 Antibody (Center)

(Mouse) Smad2 Antibody (Center)

ArtNr	ABC-AP21006a
Hersteller	Abcepta
Menge	400 ul
Kategorie	Neuroscience Neural Lineage Markers Antibodies Western Blot Primary Antibodies Neurodegeneration Markers
Typ	Antibody Polyclonal
Applikationen	WB
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Citations	Baker J.C.,et al.Genes Dev. 10:1880-1889(1996). Devereux T.R.,et al.Carcinogenesis 18:1751-1755(1997). Bernard D.J.,et al.Mol. Endocrinol. 18:606-623(2004). Carninci P.,et al.Science 309:1559-1563(2005). Weinstein M.,et al.Cytokine Growth Factor Rev. 11:49-58(2000).
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Mothers against decapentaplegic homolog 2,MAD homolog 2,Mothers against DPP homolog 2,Mad-related protein 2,mMad2,SMAD family member 2,SMAD 2,Smad2,Smad2,Madh2,Madr2
Similar products	Smad2, Mothers against DPP homolog 2, SMAD 2, Mothers against decapentaplegic homolog 2, MAD homolog 2, Mad-related protein 2, SMAD family member 2, Madh2, Madr2, mMad2
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Manufacturer - Category	Primary Antibodies; Cancer; Signal Transduction; Stem Cells
Manufacturer - Targets	This mouse Smad2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 198-232 amino acids from the Central region of mouse Smad2.
Bio Background	Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator (By similarity).
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB51534
Gene Name	Smad2
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H, M, Rat
Predicted Reactivity	B, C, Pig
Calculated Molecular Weight	52266
Antigen Source	HUMAN
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	WB: 1:500-1:1000

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Menge: 400 ul

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