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ASH2L Antibody (Center)

ASH2L Antibody (Center)

ArtNr	ABC-AP21332c
Hersteller	Abcepta
Menge	400 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen	WB
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	ASH2L, ASH2L1, Set1/Ash2 histone methyltransferase complex subunit ASH2, ASH2-like protein
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Primary Accession	Q9UBL3
Application	WB
Bio Background	Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. May function as a transcriptional regulator. May play a role in hematopoiesis.
Bio References	Wang J., et al.J. Mol. Med. 79:399-405(2001). Ikegawa S., et al.Cytogenet. Cell Genet. 84:167-172(1999). Ota T., et al.Nat. Genet. 36:40-45(2004). Mural R.J., et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases. Wysocka J., et al.Genes Dev. 17:896-911(2003).
Clonality	polyclonal
Clone/Animal Names	RB52789
Gene ID	9070
Gene Name	ASH2L
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	M
Legend image 1	All lanes : Anti-ASH2L Antibody (Center) at 1:2000 dilution Lane 1: Hela whole cell lysates Lane 2: Jurkat whole cell lysates Lane 3: K562 whole cell lysates Lane 4: F9 whole cell lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 69 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Type image 1	WB
Dilution image 1	1:2000
Legend image 2	All lanes : Anti-ASH2L Antibody (Center) at 1:2000 dilution + NIH/3T3 whole cell lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 69 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Type image 2	WB
Dilution image 2	1:2000
Isotype	Rabbit Ig
Calculated MW	68723
Antigen Source	HUMAN
Target/Specificity	This ASH2L antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 347-382 amino acids from the Central region of human ASH2L.

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ABC-AP21332c-datasheet.pdf

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Menge: 400 ul

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