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PHC1 Antibody (N-Term)

PHC1 Antibody (N-Term)

ArtNr	ABC-AP21886a
Hersteller	Abcepta
Menge	200 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen	WB
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	PHC1, PH1, EDR1, Early development regulatory protein 1, hPH1, Polyhomeotic-like protein 1
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Primary Accession	P78364
Application	WB
Bio Background	Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Required for proper control of cellular levels of GMNN expression.
Bio References	Gunster M.J., et al.Mol. Cell. Biol. 17:2326-2335(1997). Scherer S.E., et al.Nature 440:346-351(2006). Mural R.J., et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases. Satijn D.P.E., et al.Mol. Cell. Biol. 17:4105-4113(1997). Levine S.S., et al.Mol. Cell. Biol. 22:6070-6078(2002).
Clonality	polyclonal
Clone/Animal Names	RB54227
Gene ID	1911
Gene Name	PHC1
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	All lanes : Anti-PHC1 Antibody (N-Term) at 1:2000 dilution Lane 1: Hela whole cell lysate Lane 2: Jurkat whole cell lysate Lane 3: NCCIT whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 103 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Type image 1	WB
Dilution image 1	1:2000
Other Accession	Q64028
Predicted	M
Isotype	Rabbit Ig
Calculated MW	105534
Antigen Source	HUMAN
Target/Specificity	This PHC1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 308-342 amino acids from human PHC1.

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ABC-AP21886a-datasheet.pdf

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Menge: 200 ul

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Lieferung vsl. bis 02.10.2025