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APEX1 Antibody (N-term)

APEX1 Antibody (N-term)

ArtNr	ABC-AP2849a
Hersteller	Abcepta
Menge	400 ul
Kategorie	Neuroscience Molecular Targets for Neuroscience Antibodies Western Blot Immunofluorescence Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	WB, IF
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Vascotto,C., Mol. Cell. Biol. 29 (7), 1834-1854 (2009) Li,W.Q., Carcinogenesis 30 (3), 500-505 (2009) Lo,Y.L., Cancer Epidemiol. Biomarkers Prev. 18 (1), 223-229 (2009) Bhakat,K.K., EMBO J. 22 (23), 6299-6309 (2003)
NCBI	NP_001231178.1,NP_001632.2,NP_542379.1,NP_542380.1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	DNA-(apurinic or apyrimidinic site) lyase,31--,APEX nuclease,APEN,Apurinic-apyrimidinic endonuclease 1,AP endonuclease 1,APE-1,REF-1,Redox factor-1,DNA-(apurinic or apyrimidinic site) lyase,mitochondrial,APEX1,APE,APE1,APEX,APX,HAP1,REF1
Similar products	APE1, HAP1, APEX1, mitochondrial, APE, APEN, APEX, APX, REF1, DNA-(apurinic or apyrimidinic site) lyase, AP endonuclease 1, APE-1, APEX nuclease, Apurinic-apyrimidinic endonuclease 1, Redox factor-1, REF-1, 31--
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Manufacturer - Category	Primary Antibodies; Cardiovascular; Mitochondrion
Manufacturer - Targets	This APEX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-64 amino acids from the N-terminal region of human APEX1.
Bio Background	Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This protein is the major AP endonuclease in human cells.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB17544
Gene Name	APEX1
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Calculated Molecular Weight	35555
Antigen Source	HUMAN
Antigen Region	30-64
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Dilution	IF: 1:10~50 WB: 1:1000 WB: 1:1000
Antigen Type	Synthetic Peptide

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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ABC-AP2849a-datasheet.pdf

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Menge: 400 ul

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Lieferung vsl. bis 05.03.2026

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