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Phospho-Rb(S811) Antibody

Phospho-Rb(S811) Antibody

ArtNr	ABC-AP3241a
Hersteller	Abcepta
Menge	400 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen	IF, IHC-P, Dot
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	Rb, RB1, Retinoblastoma-associated protein, p105-Rb, pRb, pp110
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Primary Accession	P06400
Antigen Type	Synthetic Peptide
Application	IF, IHC-P, DB
Bio Background	Retinoblastoma (RB) is an embryonic malignant neoplasm of retinal origin. It almost always presents in early childhood and is often bilateral. Spontaneous regression occurs in some cases.
Bio References	Dasgupta, P., et al., Mol. Cell. Biol. 24(21):9527-9541 (2004). Cui, X., et al., Hum. Pathol. 35(10):1189-1195 (2004). Borah, S., et al., J. Virol. 78(19):10336-10347 (2004). Dasgupta, P., et al., J. Biol. Chem. 279(37):38762-38769 (2004). Lohmann, D.R., et al., J. Biol. Chem. 129(1):23-28 (2004).
Clonality	Polyclonal
Clone/Animal Names	RB7679
Gene ID	5925
Gene Name	RB1
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Confocal immunofluorescent analysis of Phospho-Rb-S811 Antibody(Cat#AP3241a) with HepG2 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).DAPI was used to stain the cell nuclear (blue).
Type image 1	IF
Dilution image 1	1:10~50
Legend image 2	Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Type image 2	IHC-P
Dilution image 2	1:50~100
Legend image 3	Dot blot analysis of anti-hRb-S811 Phospho-specific Pab (Cat. #AP3241a) on nitrocellulose membrane. 50ng of nonphospho-peptide or phospho-peptide were adsorbed on their respective dots. Antibody working concentration was 0.5ug per ml.
Type image 3	DB
Dilution image 3	1:500
Other Accession	P33568; P13405
Predicted	M, Rat
Isotype	Rabbit Ig
Calculated MW	106159
Antigen Source	HUMAN
Target/Specificity	This Rb Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S811 of human Rb.
NCBI Accession	NP_000312.2

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ABC-AP3241a-datasheet.pdf

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Menge: 400 ul

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Lieferung vsl. bis 04.09.2025