Phospho-SMAD4(T277) Antibody

ArtNr	ABC-AP3251a
Hersteller	Abcepta
Menge	400 ul
Kategorie	Oncology Neuroscience Targets for Rodent Neurosciences Antibodies By Cell Type Carcinoma Adenocarcinoma Western Blot Primary Antibodies By Organ Colorectal Cancer
Typ	Antibody Polyclonal
Applikationen	WB
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Citations	Sekiya, T., et al., Biochem. Biophys. Res. Commun. 320(3):680-684 (2004). Horvath, L.G., et al., Prostate 59(3):234-242 (2004). Li, L., et al., Mol. Cell. Biol. 24(2):856-864 (2004). Wan, M., et al., J. Biol. Chem. 279(15):14484-14487 (2004). Maru, D., et al., Oncogene 23(3):859-864 (2004).
NCBI	NP_005350.1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Mothers against decapentaplegic homolog 4,MAD homolog 4,Mothers against DPP homolog 4,Deletion target in pancreatic carcinoma 4,SMAD family member 4,SMAD 4,Smad4,hSMAD4,SMAD4,DPC4,MADH4
Similar products	SMAD4, Smad4, DPC4, MADH4, MAD homolog 4, Deletion target in pancreatic carcinoma 4, SMAD family member 4, Mothers against decapentaplegic homolog 4, Mothers against DPP homolog 4, SMAD 4, hSMAD4
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Manufacturer - Category	Primary Antibodies; Antibody Collections; Cancer; Cardiovascular; Metabolism; Signal Transduction; Phospho Antibodies; Anti-Wnt-Pathway (plus Lgr5) Antibodies; SARS-Human interaction partners
Manufacturer - Targets	This SMAD4 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T277 of human SMAD4.
Bio Background	Common mediator of signal transduction by TGF-beta (transforming growth factor) superfamily, SMAD4 is the common SMAD (co-SMAD). It promotes binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides an activation function required for SMAD1 or SMAD2 to stimulate transcription. It may act as a tumor suppressor.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB07971
Gene Name	SMAD4
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H, M
Predicted Reactivity	Rat
Calculated Molecular Weight	60439
Antigen Source	HUMAN
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	WB: 1:500
Antigen Type	Synthetic Peptide

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Menge: 400 ul

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