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Phospho-EIF4EBP1(T36) Antibody

ArtNr ABC-AP3417a
Hersteller Abcepta
Menge 400 ul
Kategorie
Typ Antibody Polyclonal
Applikationen Dot
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Citations Fonseca,B.D., J. Biol. Chem. 282 (34), 24514-24524 (2007)
Armengol,G., Cancer Res. 67 (16), 7551-7555 (2007)
NCBI NP_004086.1
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Eukaryotic translation initiation factor 4E-binding protein 1,4E-BP1,eIF4E-binding protein 1,Phosphorylated heat- and acid-stable protein regulated by insulin 1,PHAS-I,EIF4EBP1
Similar products 4E-BP1, EIF4EBP1, Eukaryotic translation initiation factor 4E-binding protein 1, Phosphorylated heat- and acid-stable protein regulated by insulin 1, PHAS-I, eIF4E-binding protein 1
Lieferbar
Manufacturer - Category
Primary Antibodies; Antibody Collections; Metabolism; Phospho Antibodies
Manufacturer - Targets
This EIF4EBP1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T36 of human EIF4EBP1.
Bio Background
EIF4EBP1 is a member of a family of translation repressor proteins. This protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 4S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. It is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.
Clonality
Polyclonal
Polyclonal Antibody Additonal Information
RB11405
Gene Name
EIF4EBP1
Subtitle
Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H
Predicted Reactivity
B, M, Rat
Calculated Molecular Weight
12580
Antigen Source
HUMAN
Formulation
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution
DB: 1:500
Antigen Type
Synthetic Peptide

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 400 ul
Lieferbar: In stock
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