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Phospho-MAP4K4(S629) Antibody

Phospho-MAP4K4(S629) Antibody

ArtNr	ABC-AP3428a-ev
Hersteller	Abcepta
Menge	80 ul
Kategorie	Antibodies Western Blot Primary Antibodies Dot Blot
Typ	Antibody Polyclonal
Applikationen	WB, Dot
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Wright, J.H., et al., Mol. Cell. Biol. 23(6):2068-2082 (2003). Yao, Z., et al., J. Biol. Chem. 274(4):2118-2125 (1999). Ishikawa, K., et al., DNA Res. 5(3):169-176 (1998).
NCBI	NP_001229488.1,NP_004825.3,NP_663720.1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Mitogen-activated protein kinase kinase kinase kinase 4,HPK/GCK-like kinase HGK,MAPK/ERK kinase kinase kinase 4,MEK kinase kinase 4,MEKKK 4,Nck-interacting kinase,MAP4K4,HGK,KIAA0687,NIK
Similar products	NIK, HGK, MAP4K4, Mitogen-activated protein kinase kinase kinase kinase 4, HPK/GCK-like kinase HGK, MAPK/ERK kinase kinase kinase 4, Nck-interacting kinase, KIAA0687, MEKKK 4, MEK kinase kinase 4
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Manufacturer - Category	Primary Antibodies; Antibody Collections; Signal Transduction; Phospho Antibodies
Manufacturer - Targets	This Phospho-MAP4K4-pS629 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S629 of human MAP4K4.
Bio Background	M4K4, a member of the STE2 subfamily of Ser/Thr protein kinases, may play a role in the response to environmental stress and cytokines such as TNF-alpha. It appears to act upstream of the JUN N-terminal pathway. This protein is thought to interact with the SH3 domain of the adapter proteins Nck. HGK binds, via its CNH regulatory domain, to the N-terminal region of SPG3A. Expression appears to be ubiquitous, expressed in all tissue types examined. Isoform 5 appears to be more abundant in the brain, and isoform 4 is predominant in the liver, skeletal muscle and placenta.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB12877
Gene Name	MAP4K4
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Calculated Molecular Weight	142101
Antigen Source	HUMAN
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	DB: 1:500
Antigen Type	Synthetic Peptide

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 80 ul

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Lieferung vsl. bis 01.01.2026

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