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Phospho-ACK1(Y826) Antibody

ArtNr ABC-AP3702a
Hersteller Abcepta
Menge 400 ul
Kategorie
Typ Antibody Polyclonal
Applikationen Dot
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Citations Guo A, et al. (2008) A 105, 692-7
Rikova K, et al. (2007) Cell 131, 1190-203
Huang PH, et al. (2007) Proc Natl Acad Sci U S A 104, 12867-72
Wolf-Yadlin A, Hautaniemi S, Lauffenburger DA, White FM (2007) Proc Natl Acad Sci U S A 104, 5860-5
Goss VL, et al. (2006) Blood 107, 4888-97
Wolf-Yadlin A, et al. (2006) Mol Syst Biol 2, 54
Rush J, et al. (2005) Nat Biotechnol 23, 94-101
NCBI NP_001010938.1,NP_005772.3
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Activated CDC42 kinase 1,ACK-1,Tyrosine kinase non-receptor protein 2,TNK2,ACK1
Similar products ACK-1, TNK2, ACK1, Activated CDC42 kinase 1, Tyrosine kinase non-receptor protein 2
Lieferbar
Manufacturer - Category
Primary Antibodies; Antibody Collections; Cancer; Signal Transduction; Phospho Antibodies; Anti-Kinome Antibodies
Manufacturer - Targets
This ACK1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y826 of human ACK1.
Bio Background
ACK1 is a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway.
Clonality
Polyclonal
Polyclonal Antibody Additonal Information
RB15411
Gene Name
TNK2
Subtitle
Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H
Predicted Reactivity
B, M, Rat
Calculated Molecular Weight
114569
Antigen Source
HUMAN
Formulation
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution
DB: 1:500
Antigen Type
Synthetic Peptide

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 400 ul
Lieferbar: In stock
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