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Phospho-SQSTM1(S207) Antibody

Phospho-SQSTM1(S207) Antibody

ArtNr	ABC-AP3801a
Hersteller	Abcepta
Menge	400 ul
Kategorie	Oncology Neuroscience Protein Aggregation, Clearance & Misfolding Antibodies By Cell Type Carcinoma Cell Biology Cell Status Adenocarcinoma Autophagy Primary Antibodies Dot Blot
Typ	Antibody Polyclonal
Applikationen	Dot
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Visconti, M.R., et al. J. Bone Miner. Res. 25(11):2368-2373(2010) Ding, W.X., et al. J. Biol. Chem. 285(36):27879-27890(2010) Gao, C., et al. Nat. Cell Biol. 12(8):781-790(2010) Jain, A., et al. J. Biol. Chem. 285(29):22576-22591(2010) Lau, A., et al. Mol. Cell. Biol. 30(13):3275-3285(2010)
NCBI	NP_001135770.1,NP_001135771.1,NP_003891.1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Sequestosome-1,EBI3-associated protein of 60 kDa,EBIAP,p60,Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa,Ubiquitin-binding protein p62,SQSTM1,ORCA,OSIL
Similar products	SQSTM1, p60, ORCA, OSIL, Sequestosome-1, EBI3-associated protein of 60 kDa, Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa, Ubiquitin-binding protein p62, EBIAP
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Manufacturer - Category	Primary Antibodies; Antibody Collections; Cardiovascular; Metabolism; Signal Transduction; Phospho Antibodies; Immunity; Autophagy; Lysosome; SARS-Human interaction partners
Manufacturer - Targets	This SQSTM1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S207 of human SQSTM1.
Bio Background	This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB40754
Gene Name	SQSTM1 {ECO:0000303\|PubMed:16286508, ECO:0000312\|HGNC:HGNC:11280}
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Calculated Molecular Weight	47687
Antigen Source	HUMAN
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	DB: 1:500
Antigen Type	Synthetic Peptide

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 400 ul

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