Vergleich

Phospho-EP300(S1834) Antibody

ArtNr ABC-AP3842a
Hersteller Abcepta
Menge 400 ul
Kategorie
Typ Antibody Polyclonal
Applikationen Dot
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Citations Zhang, M., et al. J. Immunol. 185(7):3960-3969(2010)
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Vempati, R.K., et al. J. Biol. Chem. 285(37):28553-28564(2010)
Reynoird, N., et al. EMBO J. 29(17):2943-2952(2010)
Jang, E.R., et al. Biochem. Biophys. Res. Commun. 397(4):637-643(2010)
NCBI NP_001420.2
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Histone acetyltransferase p300,p300 HAT,E1A-associated protein p300,EP300,P300
Similar products EP300, P300, Histone acetyltransferase p300, E1A-associated protein p300, p300 HAT
Lieferbar
Manufacturer - Category
Primary Antibodies; Antibody Collections; Cancer; Metabolism; Signal Transduction; Phospho Antibodies; Anti-Wnt-Pathway (plus Lgr5) Antibodies; Viral process; Host-virus interaction; Jak-STAT signaling KEGG
Manufacturer - Targets
This EP300 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S1834 of human EP300.
Bio Background
This gene encodes the adenovirus E1A-associated cellularp3 transcriptional co-activator protein. It functions as histoneacetyltransferase that regulates transcription via chromatinremodeling and is important in the processes of cell proliferationand differentiation. It mediates cAMP-gene regulation by bindingspecifically to phosphorylated CREB protein. This gene has alsobeen identified as a co-activator of HIF1A (hypoxia-induciblefactor 1 alpha), and thus plays a role in the stimulation ofhypoxia-induced genes such as VEGF. Defects in this gene are acause of Rubinstein-Taybi syndrome and may also play a role inepithelial cancer.
Clonality
Polyclonal
Polyclonal Antibody Additonal Information
RB41431
Gene Name
EP300 {ECO:0000303|PubMed:15706485, ECO:0000312|HGNC:HGNC:3373}
Subtitle
Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H
Calculated Molecular Weight
264161
Antigen Source
HUMAN
Formulation
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution
DB: 1:500
Antigen Type
Synthetic Peptide

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 400 ul
Lieferbar: In stock
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