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HSPA5 Antibody (Center)

HSPA5 Antibody (Center)

ArtNr	ABC-AP5041c-ev
Hersteller	Abcepta
Menge	80 ul
Kategorie	Oncology Antibodies By Cell Type Hematology Myeloma Immunohistochemistry Western Blot Immunofluorescence Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	WB, IF, IHC-P
Specific against	Human (Homo sapiens), Zebrafish (Danio rerio)
Host	Rabbit
Isotype	IgG
Citations	Zhao, C., et al. J. Med. Virol. 82(1):14-22(2010) Zhuang, L., et al. Mod. Pathol. 23(1):45-53(2010) Arnaudeau, S., et al. Proteomics 9(23):5316-5327(2009)
NCBI	NP_005338.1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	78 kDa glucose-regulated protein,GRP-78,Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78,Heat shock 70 kDa protein 5,Immunoglobulin heavy chain-binding protein,BiP,HSPA5,GRP78
Similar products	GRP-78, HSPA5, GRP78, 78 kDa glucose-regulated protein, Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78, Heat shock 70 kDa protein 5, Immunoglobulin heavy chain-binding protein, BiP
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Manufacturer - Category	Primary Antibodies; Antibody Collections; Zebrafish; Apoptosis signaling
Manufacturer - Targets	This HSPA5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 261-289 amino acids from the Central region of human HSPA5.
Bio Background	When Chinese hamster K12 cells are starved of glucose, the synthesis of several proteins, called glucose-regulated proteins (GRPs), is markedly increased. Hendershot et al. (1994) [PubMed 82977] pointed out that one of these, GRP78 (HSPA5), also referred to as 'immunoglobulin heavy chain-binding protein' (BiP), is a member of the heat-shock protein-7 (HSP7) family and is involved in the folding and assembly of proteins in the endoplasmic reticulum (ER). Because so many ER proteins interact transiently with GRP78, it may play a key role in monitoring protein transport through the cell.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB20813
Gene Name	HSPA5
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H, Zf
Predicted Reactivity	B, C, Ha, M, Rat
Calculated Molecular Weight	72333
Antigen Source	HUMAN
Antigen Region	261-289
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	IF: 1:10~50 WB: 1:1000 WB: 1:1000 IHC-P: 1:50~100
Antigen Type	Synthetic Peptide

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