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XRCC6 Antibody (Center)

XRCC6 Antibody (Center)

ArtNr	ABC-AP5089c-ev
Hersteller	Abcepta
Menge	80 ul
Kategorie	Oncology Antibodies By Cell Type Carcinoma Melanoma Flow Cytometry Immunohistochemistry Western Blot Immunofluorescence Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	WB, FC, IF, IHC-P
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Liu, Y., et al. Carcinogenesis 31(10):1762-1769(2010) Briggs, F.B., et al. Am. J. Epidemiol. 172(2):217-224(2010) Pace, P., et al. Science 329(5988):219-223(2010) Sobczuk, A., et al. Pol J Pathol 61(1):27-31(2010)
NCBI	NP_001460.1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	Ku70, G22P1, XRCC6, 70 kDa subunit of Ku antigen, CTC75, CTCBF, DNA repair protein XRCC6, Lupus Ku autoantigen protein p70, TLAA, X-ray repair cross-complementing protein 6, 364-, Thyroid-lupus autoantigen, 5'-deoxyribose-5-phosphate lyase Ku70, 5'-dRP lyase Ku70, X-ray repair complementing defective repair in Chinese hamster cells 6, ATP-dependent DNA helicase 2 subunit 1, ATP-dependent DNA helicase II 70 kDa subunit, CTC box-binding factor 75 kDa subunit, 4299-
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Manufacturer - Category	Crown Antibodies; Primary Antibodies; Cancer
Manufacturer - Targets	This XRCC6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 228-254 amino acids from the Central region of human XRCC6.
Bio Background	The p7/p8 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 7 and 8 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p7 and p8 have been found in some patients with systemic lupus erythematosus.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB22956
Gene Name	XRCC6
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Calculated Molecular Weight	69843
Antigen Source	HUMAN
Antigen Region	228-254
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	IF: 1:10~50 WB: 1:1000 IHC-P: 1:50~100 FC: 1:10~50
Antigen Type	Synthetic Peptide
Manufacturer - Alias	X-ray repair cross-complementing protein 6, 364-, 4299-, 5'-deoxyribose-5-phosphate lyase Ku70, 5'-dRP lyase Ku70, 70 kDa subunit of Ku antigen, ATP-dependent DNA helicase 2 subunit 1, ATP-dependent DNA helicase II 70 kDa subunit, CTC box-binding factor 75 kDa subunit, CTC75, CTCBF, DNA repair protein XRCC6, Lupus Ku autoantigen protein p70, Ku70, Thyroid-lupus autoantigen, TLAA, X-ray repair complementing defective repair in Chinese hamster cells 6, XRCC6, G22P1
Manufacturer - Similar	X-ray repair cross-complementing protein 6, 364-, 4299-, 5'-deoxyribose-5-phosphate lyase Ku70, 5'-dRP lyase Ku70, 70 kDa subunit of Ku antigen, ATP-dependent DNA helicase 2 subunit 1, ATP-dependent DNA helicase II 70 kDa subunit, CTC box-binding factor 75 kDa subunit, CTC75, CTCBF, DNA repair protein XRCC6, Lupus Ku autoantigen protein p70, Ku70, Thyroid-lupus autoantigen, TLAA, X-ray repair complementing defective repair in Chinese hamster cells 6, XRCC6, G22P1

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Menge: 80 ul

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