MAP3K11 Antibody

ArtNr	ABC-AP5174d-ev
Hersteller	Abcepta
Menge	80 ul
Kategorie	Oncology Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Lymphoma Myeloma Melanoma Sarcoma Western Blot Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	WB
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Citations	Rangasamy, V., et al. Cancer Res. 70(4):1731-1740(2010) Velho, S., et al. Hum. Mol. Genet. 19(4):697-706(2010) Cole, E.T., et al. Biochim. Biophys. Acta 1793(12):1811-1818(2009)
NCBI	NP_002410.1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Mitogen-activated protein kinase kinase kinase 11,Mixed lineage kinase 3,Src-homology 3 domain-containing proline-rich kinase,MAP3K11 ()
Similar products	Mitogen-activated protein kinase kinase kinase 11, Mixed lineage kinase 3, Src-homology 3 domain-containing proline-rich kinase, MAP3K11 (HGNC:6850)
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Manufacturer - Category	Primary Antibodies; Signal Transduction
Manufacturer - Targets	This MAP3K11 antibody is generated from rabbits immunized with MAP3K11 recombinant protein.
Bio Background	MAP3K11 is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB22172
Gene Name	MAP3K11
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H, M
Calculated Molecular Weight	92688
Antigen Source	HUMAN
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	WB: 1:1000
Antigen Type	Recombinant Protein

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